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pentobarbital will decrease the level or impact of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital raises toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers could improve the metabolism of ifosfamide to its Lively